Researchers develop new device to help image key proteins at room temperature

A group of researchers from Arizona State University are part of a larger team reporting a major advance in the study of human proteins that could open up new avenues for more effective drugs of the future. The work is…

A group of researchers from Arizona State University are part of a larger team reporting a major advance in the study of human proteins that could open up new avenues for more effective drugs of the future. The work is being reported in this week’s Science magazine.

In the paper, “Serial femtosecond crystallography of G-protein-coupled receptors,” the team reports that they have been successful in imaging at room temperature the structure of G protein-coupled receptors (GPCR) with the use of an x-ray free-electron laser.

GPCR’s are a highly diverse group of membrane proteins that mediate cellular communication. Because of their involvement in key physiological and sensory processes in humans, they are thought to be prominent drug targets.

Read more at: http://phys.org/news/2013-12-device-image-key-proteins-room.html#jCp