$2.5 million for innovative systems biology research

Document Type: Grants Notice Funding Opportunity Number: 12-577 Opportunity Category: Discretionary Posted Date: Jun 29, 2012 Creation Date: Jun 29, 2012 Original Closing Date for Applications: Dec 03, 2012    Preliminary Proposal Due Date(s) (required) (due by 5 p.m. proposer’s…
Document Type: Grants Notice
Funding Opportunity Number: 12-577
Opportunity Category: Discretionary
Posted Date: Jun 29, 2012
Creation Date: Jun 29, 2012
Original Closing Date for Applications: Dec 03, 2012    Preliminary Proposal Due Date(s) (required) (due by 5 p.m. proposer’s local time): September 04, 2012 Full Proposal Deadline(s): December 03, 2012
Current Closing Date for Applications: Dec 03, 2012    Preliminary Proposal Due Date(s) (required) (due by 5 p.m. proposer’s local time): September 04, 2012 Full Proposal Deadline(s): December 03, 2012
Archive Date: Jan 03, 2013
Funding Instrument Type: Grant
Category of Funding Activity: Science and Technology and other Research and Development
Category Explanation:
Expected Number of Awards: 40
Estimated Total Program Funding: $2,500,000
Award Ceiling: $230,000
Award Floor:
CFDA Number(s): 47.074  —  Biological Sciences
Cost Sharing or Matching Requirement: No

Eligible Applicants

Others (see text field entitled “Additional Information on Eligibility” for clarification)

Additional Information on Eligibility:

*Organization Limit: Proposals may only be submitted by the following: -Non-profit, non-academic organizations: Independent museums, observatories, research labs, professional societies and similar organizations in the U.S. associated with educational or research activities. -Universities and Colleges – Universities and two- and four-year colleges (including community colleges) accredited in, and having a campus located in the US, acting on behalf of their faculty members. Such organizations also are referred to as academic institutions.

Agency Name

National Science Foundation

Description

The National Science Foundation (NSF) is partnering with the United States-Israel Binational Science Foundation (BSF) to support collaborative research between US and Israeli investigators in areas of biology supported by the NSF Division of Integrative Organismal Systems. The Division of Integrative Organismal Systems (IOS) supports research aimed at an integrative understanding of organisms. The goal is to predict why organisms are structured the way they are, and function as they do. Projects that innovatively apply systems biology approaches, i.e. approaches that combine experimentation, computation, and modeling, and which lead to new conceptual and theoretical insights and predictions about integrated organismal properties that may be experimentally verified, are particularly encouraged. In the context of greater accessibility to ever-expanding and increasingly detailed biological information, the overriding objective of IOS is to support research to understand the fundamental nature of life by understanding the emergent properties of organisms. Some of these properties include but are not restricted to: complexity (how interwoven organismal components or processes produce more than a sum of their parts), robustness (the degree to which an organism resists perturbation or stressful influences); communication (the processes that enable individual components in a system to instruct one another or alter one another’s behavior); resilience (the ability to recover from perturbation or stress), adaptability (the capacity of organisms to change in response to perturbations in ways that maintain overall organismal integrity), and cooperation (behaviors of cells or organisms that benefit more than the individual). These emergent properties can be understood through studies of the evolution, development, behavior, regulatory processes and structural properties of all organisms. Therefore comparative studies and the use of a wide variety of organisms as models are encouraged. Understanding these emergent, systems properties of organisms requires integrative, interdisciplinary approaches. The Division encourages proposals that include analyses across multiple levels of biological organization, from molecular through ecological, theoretical as well as advanced computational techniques, and interdisciplinary collaborations involving scientists from all areas of biology, behavioral science, physical science, mathematics, engineering, and computer science. The scientific emphases of IOS are: BEHAVIORAL SYSTEMS; DEVELOPMENTAL SYSTEMSl; NEURAL SYSTEMS; PHYSIOLOGICAL AND STRUCTURAL SYSTEMS; PLANT GENOME RESEARCH. BSF supports a wide range of basic research, including the areas of biology supported by IOS. Proposers are encouraged to consult the IOS (http://www.nsf.gov/div/index.jsp?org=IOS) and BSF (http://www.bsf.org.il/BSFPublic/Default.aspx) program descriptions prior to development of a proposal. Proposals are expected to inlcude substantial collaborative activites between US and Israeli investigators. Proposers are strongly encouraged to develop joint activities that are syngergistic and have added value over and above individual activities. Proposals that address aspects of organism-enviroment interactions and organismal adaptation are especially encouraged.